Try deactivating grass, sky and dynamic hair in the graphics options. Unity HDRP requires a graphics card with at least 2 GB VRAM, DirectX11 and Shader Model 5.0. The game does not work with CPU-integrated graphics cards.
For simple items (potions, arrows), open your inventory and drag, for example, a basic potion (the white one) onto a flower.For more complex items, use the workshop in the house. https://www.saeder.ch/index.php/the-game/items/